• evasive_chimpanzee@lemmy.world
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    5 days ago

    Hormone imbalances can’t overcome thermodynamics. In people with hypothyroidism, the set point of their resting metabolic rate is lower, leading to fatigue and often being too cold.

    So it’s not that they gain weight despite a deficit, it’s that a deficit for them would be less calories than someone with more activity who isnt cold all the time.

    In a perfect world, calorie needs match with hunger, so with decreased calorie needs, you would naturally eat less, but it’s not always perfect so some people with hypothyroidism have “normal” hunger when they actually need less food. It ends up with 1/4-1/2 of people with hypothyroidism experiencing weight gain.